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Case of the Week 276

 


What's the most likely diagnosis?

  • 59 year-old male with change in bowel habits

  1. Carcinoma of the colon
  2. Bilateral renal calculi
  3. Cirrhosis
  4. Myelolipomas
  5. Bilateral adrenal calcifications


Answer:

 


5. Bilateral Adrenal Calcifications

 

 

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Adrenal calcifications

General Considerations

  • Hemorrhage is the most common cause
  • Generally, patients with non-traumatic adrenal hemorrhage are critically ill and have a coagulopathy
  • Adrenal glands are proportionately larger in neonates than adults and prone to complications from hypoxia or hypotension
  • Unilateral 80% of time and involves right side 85% of time
  • Unilateral adrenal hemorrhage rarely produces clinical findings
    • In adults, it is frequently found incidentally in trauma
  • Most (90%) of adrenal tissue must be destroyed for adrenal insufficiency
  • Adrenal hemorrhage is prognostically important because it may signify severe stress or unsuspected coagulopathy

 

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